Fmoc-R-3-Amino-3-(3-fluoro-phenyl)-propionic acid is an organic compound commonly used as a protecting group for peptide synthesis. The following is a description of its nature, use, preparation and safety information:
Nature:
-Chemical formula: C19H15FNO3
-Molecular weight: 329.3g/mol
-Appearance: White solid
-Melting point: 159-160°C
-Solubility: better solubility in organic solvents
Use:
- Fmoc-R-3-Amino-3-(3-fluoro-phenyl)-propionic acid is one of the commonly used protected amino acids in peptide synthesis. By attaching it to the N-terminus of the amino acid chain, the reactivity of the amino acid can be protected for subsequent chemical reactions.
Preparation Method:
The synthesis of-Fmoc-R-3-Amino-3-(3-fluoro-phenyl)-propionic acid is usually carried out by chemical synthetic routes. The specific synthetic method may vary from case to case, but a general procedure involves the synthesis of 3-amino -3-(3-fluorophenyl) propionic acid, which is then attached to the Fmoc protecting group.
Safety Information:
- Fmoc-R-3-Amino-3-(3-fluoro-phenyl)-propionic acids are generally chemicals and need to comply with relevant laboratory operations and safety measures. It may be irritating to the eyes, skin and respiratory system. When operating, wear appropriate personal protective equipment to avoid inhalation, contact and ingestion. During use and storage, attention should be paid to fire and explosion prevention and avoid mixing with other chemicals.
Please operate carefully in a laboratory environment and refer to the safety data sheet and operation manual provided by the supplier according to the specific situation.